Integration of selective internal radiation therapy second-line: The InSIRT trial
نویسندگان
چکیده
منابع مشابه
Selective internal radiation therapy for liver tumours.
Primary and secondary liver malignancies are common and associated with a poor prognosis. Surgical resection is the treatment of choice; however, many patients have unresectable disease. In these cases, several liver directed therapies are available, including selective internal radiation therapy (SIRT). SIRT is a multidisciplinary treatment involving nuclear medicine, interventional radiology ...
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Image-guided interstitial brachytherapy is used for the treatment of primary and secondary liver tumors. Millions of nonbiodegradable yttrium-90 (90Y)-imprinted microspheres with a diameter of 29– 35 μmare selectively infused by a catheter into the branch of the hepatic artery supplying the tumor. Thereby, a radiation dose of 30–60Gy can be applied to the tumor tissue. 90Y is a beta-emitter wit...
متن کاملOptimization of Bremsstrahlung imaging in Yttrium internal radiation therapy
Introduction: Treatment efficacy of radiation therapy using Yttrium-90 radionuclide is evaluated by the bremsstrahlung SPECT imaging following radiation therapy. The radioisotopic images have the ability to provide reliable activity map of 90Y distribution. But these images have a low quantitative accuracy in the 90Y bremsstrahlung SPECT imaging, therefore the optimization of...
متن کاملModeling Internal Radiation Therapy
A new technique is described to model (internal) radiation therapy. It is founded on morphological processing, in particular distance transforms. Its formal basis is presented as well as its implementation via the Fast Exact Euclidean Distance (FEED) transform. Its use for all variations of internal radiation therapy is described. In a benchmark trial, FEED proved to be truly exact as well as f...
متن کاملSelective Internal Radiation Therapy (SIRT) as Conversion Therapy for Unresectable Primary Liver Malignancies.
BACKGROUND Many patients with primary liver cancers are not candidates for surgery, and systemic therapies are seldom effective. Selective internal radiation therapy (SIRT) has been shown to obtain partial and even complete response in unresectable primary tumors. As a "side effect", SIRT can induce contra-lateral liver hypertrophy. Tumor response to SIRT can be sufficient to allow disengagemen...
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ژورنال
عنوان ژورنال: European Journal of Cancer Supplements
سال: 2012
ISSN: 1359-6349
DOI: 10.1016/s1359-6349(12)70032-0